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Test for determining the leakage of amniotic fluid

Leakage of amniotic fluid can occur at various stages of pregnancy and may indicate various underlying conditions. At the "Dobrobut" Medical Center, experienced doctors perform tests that help determine whether there is leakage and choose the optimal strategy for managing the pregnancy and childbirth.

Service prices:

  • Testing to reveal amniotic fluid leakage (test cost excluded)
    720 uah
  • Consultation by obstetrician-gynaecologist
    1530 uah
  • Single Pregnancy Basic Program
    42980 uah

Causes of Amniotic Fluid Leakage

If the amniotic sac (amniotic membrane) ruptures before 37 weeks of pregnancy, it can lead to preterm labor, posing risks to the child's health due to prematurity, including respiratory issues and infections. If the amniotic sac ruptures after 37 weeks but before labor begins, it may indicate impending labor. In this case, it is necessary to monitor the amount of fluid leaking, and sometimes labor may need to be induced to prevent infection.

Causes of amniotic fluid leakage may include:

  • Infections, such as bacterial vaginosis and sexually transmitted infections (STIs). Due to the infectious process, the amniotic sac weakens, which can lead to premature rupture. Such infections include those detected later in pregnancy (post-37 weeks).
  • Trauma. Any significant abdominal trauma can cause the rupture of the amniotic membranes, resulting in fluid leakage. This may involve accidents, falls, or direct impacts to the abdominal area.
  • Excess amniotic fluid (polyhydramnios): a larger volume of amniotic fluid increases pressure on the amniotic sac, which may lead to rupture and leakage.
  • Weakness of the amniotic sac. Sometimes, the membranes can be inherently weaker and more prone to rupture under lower pressure.
  • The onset of normal labor: typically, the amniotic sac ruptures during the natural process of labor, a process known as "breaking the waters," which is a sign that labor is imminent.

Symptoms of Amniotic Fluid Leakage

Signs of amniotic fluid leakage include:

  • A sudden and continuous gush of clear or slightly colored fluid from the vagina;
  • A constant trickle of fluid from the vagina, which may be mistaken for urine or increased discharge;
  • The fluid has a different consistency and smell from urine, generally clear and odorless or has a slight sweet smell;
  • Decreased fetal movement;
  • Ultrasound signs of reduced fluid levels;
  • Suspected infection.

If there is a suspicion of amniotic fluid leakage at any stage of pregnancy, it is essential to consult a doctor immediately. Timely diagnosis and effective treatment can help reduce risks to both mother and child.

What to Do: Tests to Determine Amniotic Fluid Leakage

Tests to determine amniotic fluid leakage are designed to diagnose premature rupture of membranes (PROM), a condition in which the amniotic sac ruptures before labor begins. Identifying PROM is crucial because it can have serious consequences for the health of both the mother and the fetus, including the risk of infection and preterm delivery.

To diagnose the condition of the pregnant woman, it is important to determine whether PROM is present or if the fluid leakage is coming from another source. For this, an express test — Actim, specifically designed to identify amniotic fluid — is often performed.

Additionally, the following methods are used to determine amniotic fluid leakage:

  • Assessment of vaginal discharge and examination of the cervix for amniotic fluid accumulation in the vaginal fornix;
  • Nitrazine test — amniotic fluid has an alkaline reaction, so placing a sample of the fluid on nitrazine paper will yield a pH level above 6.5;
  • Fern test: a sample of vaginal discharge is placed on a microscope slide and allowed to dry; under the microscope, amniotic fluid forms a fern-like pattern as it dries;
  • Amnisure test: a rapid immunoassay that detects placental alpha-microglobulin-1 (PAMG-1), a protein present in amniotic fluid;
  • Actim — a common test for diagnosing PROM by detecting the presence of a specific insulin-like binding protein, insulin-like growth factor binding protein-1 (IGFBP-1), which is found in high concentrations in amniotic fluid.

How to Check for Amniotic Fluid Leakage

Tests for amniotic fluid leakage include several steps and are conducted in clinical settings according to the following plan:

  1. A sterile swab is taken from the vaginal area to collect a sample of the fluid.
  2. The swab is placed in a testing solution that extracts proteins specific to amniotic fluid.
  3. The solution is applied to a test strip containing specific antibodies that respond to the presence of IGFBP-1.
  4. After 5-10 minutes, the test strip is read. A positive result indicates the presence of IGFBP-1 and, therefore, confirms the leakage of amniotic fluid.

Advantages of the Amniotic Fluid Leakage Test

Conducting a test for amniotic fluid leakage has several advantages:

  • Rapid results: the test is evaluated within minutes, facilitating quick diagnosis and treatment.
  • Non-invasiveness: the procedure is safe and easy to perform — only a swab and test strip are needed.
  • High accuracy: tests such as Actim PROM are very sensitive and specific, reducing the likelihood of false positives or false negatives.
  • Cost-effectiveness: the test is relatively inexpensive, making it accessible for routine use.
  • Convenience: the procedure can be performed in various settings, including outpatient clinics, hospitals, and even by a gynecologist at home.

Early and accurate diagnosis enables timely medical intervention, which is crucial in reducing the risks associated with PROM, such as infection or preterm delivery.

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Test for determining the leakage of amniotic fluid

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Doctors Test for determining the leakage of amniotic fluid:
Avad Lina Mokhammedivna
Obstetrician-gynecologist; Ultrasound doctor, 23 experience (y.)
Atamanchuk Iryna Mykolaivna
Obstetrician-gynecologist; Geneticist; Reproductologist; Ultrasound doctor, 27 experience (y.)
Bondarchuk Tetiana Viktorivna
Obstetrician-gynecologist; Ultrasound doctor, 14 experience (y.)
Budchenko Maryna Anatoliivna
Obstetrician-gynecologist; Ultrasound doctor, 14 experience (y.)
Vaskovska Iryna Viacheslavivna
Obstetrician-gynecologist; Ultrasound doctor, 18 experience (y.)
Heraskevych Larysa Mykolaivna
Obstetrician-gynecologist; Ultrasound doctor, 26 experience (y.)
Holenko Roksolana Ivanivna
Obstetrician-gynecologist; Ultrasound doctor, 25 experience (y.)
Hoshchenko Kateryna Anatoliivna
Obstetrician-gynecologist; Ultrasound doctor, 16 experience (y.)
Hryshchenko Nataliia Ihorivna
Obstetrician-gynecologist; Ultrasound doctor, 10 experience (y.)
Danylenko Liudmyla Ivanivna
Obstetrician-gynecologist, 19 experience (y.)
Domnich Olena Petrivna
Obstetrician-gynecologist; Ultrasound doctor, 25 experience (y.)
Dymarska Oleksandra Zinoviivna
Obstetrician-gynecologist; Ultrasound doctor, 12 experience (y.)
Zharov Valerii Valeriiovych
Obstetrician-gynecologist; Ultrasound doctor, 20 experience (y.)
Zhuravlova Olena Mykolaivna
Obstetrician-gynecologist; Ultrasound doctor, 28 experience (y.)
Ismailov Roman Idaretdinovych
Obstetrician-gynecologist; Gynecologist-oncologist; Ultrasound doctor, 10 experience (y.)
Klimanska Nataliia Oleksandrivna
Obstetrician-gynecologist; Ultrasound doctor, 38 experience (y.)
Kovalova Hanna Olehivna
Obstetrician-gynecologist; Ultrasound doctor, 15 experience (y.)
Kovalchuk Nataliia Mykolaivna
Obstetrician-gynecologist, 21 experience (y.)
Kochishvili Zarina Zakharivna
Obstetrician-gynecologist; Ultrasound doctor, 7 experience (y.)
Krasii Lesia Vitaliivna
Obstetrician-gynecologist; Ultrasound doctor, 22 experience (y.)
Krasovska Oleksandra Volodymyrivna
Obstetrician-gynecologist, 19 experience (y.)
Malakhova Alina Serhiivna
Obstetrician-gynecologist; Ultrasound doctor, 13 experience (y.)
Malysh Alina Anatoliivna
Obstetrician-gynecologist; Ultrasound doctor,
Metreveli Yeliso Zelymkhanivna
Obstetrician-gynecologist; Ultrasound doctor, 34 experience (y.)
Moroz Nataliia Leonidivna
Obstetrician-gynecologist; Pediatric and adolescent gynecologist; Ultrasound doctor, 26 experience (y.)
Nevmerzhytska Tetiana Leonidivna
Obstetrician-gynecologist, 10 experience (y.)
Osadcha Alina Volodymyrivna
Obstetrician-gynecologist; Ultrasound doctor, 12 experience (y.)
Pankiv Hennadii Ihorovych
Obstetrician-gynecologist; Ultrasound doctor, 16 experience (y.)
Polentsova Nino Emirivna
Obstetrician-gynecologist; Ultrasound doctor, 10 experience (y.)
Rebekevsha Nila Oleksandrivna
Obstetrician-gynecologist; Ultrasound doctor, 27 experience (y.)
Romanova Maryna Yuzefivna
Obstetrician-gynecologist; Ultrasound doctor, 10 experience (y.)
Serhiienko Yevheniia Serhiivna
Obstetrician-gynecologist; Ultrasound doctor, 13 experience (y.)
Siruk Leonid Petrovych
Obstetrician-gynecologist; Ultrasound doctor, 36 experience (y.)
Stasevich Svitlana Mykhailivna
Obstetrician-gynecologist; Ultrasound doctor, 29 experience (y.)
Tarnavska Iryna Yaroslavivna
Obstetrician-gynecologist; Pediatric and adolescent gynecologist; Ultrasound doctor, 12 experience (y.)
Tolstanova Halyna Oleksandrivna
Obstetrician-gynecologist, 13 experience (y.)
Trots Liudmyla Pavlivna
Obstetrician-gynecologist; Ultrasound doctor, 38 experience (y.)
Farion Inna Dmytrivna
Obstetrician-gynecologist; Ultrasound doctor, 24 experience (y.)
Cholas Eleni Nikolaos
Obstetrician-gynecologist; Geneticist; Ultrasound doctor, 15 experience (y.)
Ellehina Anzhela Mykhailivna
Obstetrician-gynecologist; Ultrasound doctor, 28 experience (y.)
Yarova Iryna Valeriivna
Obstetrician-gynecologist; Ultrasound doctor, 23 experience (y.)
Yarosh Oksana Ivanivna
Obstetrician-gynecologist; Ultrasound doctor, 19 experience (y.)
Pokhytun Maryna Vasylivna
Obstetrician-gynecologist; Ultrasound doctor, 19 experience (y.)
Rohovets Olha Volodymyrivna
Obstetrician-gynecologist; Ultrasound doctor, 22 experience (y.)
Semeniuta Illia Oleksandrovych
Obstetrician-gynecologist, 11 experience (y.)
Petrovska Yuliia Oleksandrivna
Obstetrician-gynecologist; Reproductologist, 5 experience (y.)
Yatsura Tetiana Anatoliivna
Obstetrician-gynecologist; Ultrasound doctor, 5 experience (y.)
Horban Iryna Ihorivna
Obstetrician-gynecologist; Ultrasound doctor, 8 experience (y.)
Shevchenko Svitlana Vasylivna
Obstetrician-gynecologist, 6 experience (y.)
Pasynkova Olesia Anatoliivna
Obstetrician-gynecologist, 12 experience (y.)
Avdieieva Vira Anatoliivna
Obstetrician-gynecologist; Ultrasound doctor; Doctor of aesthetic gynecology, 20 experience (y.)
Tsyhaniuk Olha Petrivna
Obstetrician-gynecologist; Reproductologist; Ultrasound doctor, 15 experience (y.)
Konetsul Oleksandra Rostyslavivna
Obstetrician-gynecologist; Reproductologist, 4 experience (y.)
Bezkorovaina Anna Oleksandrivna
Obstetrician-gynecologist, 4 experience (y.)
Baryshnikova Oksana Pavlivna
Obstetrician-gynecologist, 9 experience (y.)
Denysenko Alina Andriivna
Obstetrician-gynecologist; Pediatric and adolescent gynecologist, 5 experience (y.)
Kladynoha Olha Oleksandrivna
Obstetrician-gynecologist, 5 experience (y.)
Kapran Anzhela Oleksandrivna
Obstetrician-gynecologist; Ultrasound doctor, 13 experience (y.)
Zhydkovska Olena Mykolaivna
Obstetrician-gynecologist; Ultrasound doctor, 22 experience (y.)
Vitiuk Alla Dmytrivna
Obstetrician-gynecologist, 24 experience (y.)
Shtopenko Olena Andriivna
Obstetrician-gynecologist, 4 experience (y.)
Clinics providing service:
“Dobrobut” Multidisciplinary Hospital 24/7 on Mykoly Bazhana avenue
Nikolai Bazhan Avenue, 12-A, Kyiv
“Dobrobut” Multidisciplinary Hospital 24/7 on Idzikowsky Family street
st. S. Idzikowsky (M. Mishinа), 3, Kyiv
“Dobrobut” Medical Center for the whole family on Olimpiyska
st. Antonovycha, 40, Kyiv
“Dobrobut” Medical Center for the whole family in Pechersk
st. Andriia Verkhohliada (M. Drahomyrova), 16-A, Kyiv
“Dobrobut” Medical Center for the whole family at Rusanivka
st. Entuziastiv, 1/2, Kyiv
“Dobrobut” Medical Center for the whole family in Brovary
st. Kievskaya, 221-B, Brovary
“Dobrobut” Medical Center for the whole family in Irpin
st. Poezii (Griboyedova), 8-А, Irpin
“Dobrobut” Medical Center for the whole family in Golosiiv
st. Samiila Kishky (Marshal Konev), 10/1, Kiev
“Dobrobut” Medical Center for the whole family in Beresteyska
st. Igor Sikorsky, 1, Kyiv
“Dobrobut” Medical Center for the whole family in Sofiivska Borshchahivka
st. Yabluneva, 26, Sofiivska Borshahivka
“Dobrobut” Medical Center for the whole family in Obolon
Volodymyra Ivasiuka (Geroyiv Stalingrada) Avenue, 16-V, Kyiv
“Dobrobut” Medical Center for the whole family in Svyatoshyn
st. Svyatoshinska, 3-B, Kyiv
“Dobrobut” Medical Center for adults in Poznyaky
st. Myshugy, 12, Kyiv
“Dobrobut” Medical Center for the whole family in Poznyaky
st. Dragomanova, 21-A, Kyiv
“Dobrobut” Medical Center for the whole family on Tatarska street
st. Tatarska, 2-E, Kyiv
“Dobrobut” Dermatology & Cosmetology Medical Center
st. Yulii Zdanovskoi (Mikhail Lomonosov), 71-G, Kiev

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Comments about: Yarova Iryna Valeriivna

Найкращий лікар. Спостерігаюсь вже років 100, не менше

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Лікарка 10 з 10. Та, з якою не відчуваєш страху, сорому, скутності. Тільки 100% довіра та розслаблення. Марина Юзефівна - топ ^_^

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Дуже уважний, професійний лікар

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Щиро дякую Ірині Миколаївні за професіоналізм, уважність і людяність! Візит пройшов легко й комфортно. Отримала вичерпні відповіді на всі запитання. Рекомендую як чудового фахівця і щиру людину!

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Хочу висловити щиру подяку лікарю Петровській Олії Олександрівні за професіоналізм, уважність та людяність. Від першої конституції я відчула турботу, підтримку та впевненість, що я в надійних руках. ...

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Лучшая

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